Feline heart disease:
HCM is diagnosed when any other disease does not cause left ventricular hypertrophy. Left ventricular hypertrophy is similar to HCM may be caused by diseases such as systemic hypertension which is most commonly associated with kidney disease or hyperthyroidism but such cases cannot properly be termed HCM. Mutations in several genes have been identified as major cause of HCM in humans. The mutations known to date are inherited as autosomal dominant traits with the variable expression and incomplete penetrance. This also means that an abnormal gene from only one parent is needed to cause the disease to develop in the child that its severity can vary and that it's possible for some people to have an HCM gene mutation but not develop the disease. The mutation is thus far identified for human HCM cause gene to produce a defective contractile protein. The resultant contractile units within the heart muscle are dysfunctional and so additional contractile units are produced by myocardium, heart muscle to compensate. The increased number of contractile units leads to wall thickening.
Common in cats:
HCM is most commonly seen in cats less than five years old, however it is by no means unusual to diagnose primary HCM for the first time in cats as old as seven to eight or even older whose hearts had appeared normal on previous echocardiograms. Familial occurrences have been observed in numerous breeds. But specific feline HCM genetic mutations have not been isolated as yet, it is appearing in families of cats, and observations that an affected offspring can be produced if there is an affected parent, strongly indicate a genetic basis. In Maine Coon cats and American Shorthairs, HCM is inherited as an autosomal dominant trait it is in humans too. In addition, the natural history of the disease and the pathology are the same as in humans. So, it is likely that the disease is caused by a mutation in a contractile protein gene.
Folic acid and heart disease:
Alcohol heart disease:
Protect Your Heart United States alone sees 100,000 excess deaths due to alcohol-related diseases every year. In UK it is one of the commonest causes of Hospital admissions. Same pattern of mortality and morbidity can be seen across the globe....
Alternative Heart Disease Remedies:
Alternative Treatment for Silent Killer The Heart and Vascular System is a very large system of body. Its primary function is to deliver food and oxygen to cells and remove cellular waste. Heart disease is usually referred as silent killer as...
Dog Heart Disease:
over the time during middle age and affecting many older dogs. Both types can end up with the same serious result which a condition is called heart failure. How to avoid hear disease Regular visits to your veterinarian could mean the difference...
Effects of Heart Disease:
flow of your blood to your heart the results can be very serious. Angina occurs when the arteries that supply blood to heart are severely blocked. Although scary, angina does not cause any permanent damage. A heart attack occurs when the arteries...
Heart disease Hereditary:
develops can be related to the presence of risks factors. For example, patients who have ischemic heart disease where the blood supply to the heart has decreased , rate at which this disease develops or progresses is influenced by many risks...
Heart disease Prevention:
may be inaccurate or incomplete. None of these methods guarantee prevention of Heart disease. Such as Control weigh, Healthy diet, Low-fat diet, Quit smoking, Physical activity, Control diabetes, Control blood pressure, Control cholesterol, Folic...
Heart Valve Disease:
heart is life's biggest sustainer. Pumping out blood through the valves to the arteries to each capillary and thus reaching out blood to the tiniest cell of our body, our hearts are more than responsible for each one of us being up and about. Valves...
Ischemic heart disease:
A Different Kind of Heart Ache Remember that pain in your heart… the one you had when you first saw your partner? The slow throb when he or she was hesitating to say yes to your proposal? Those are wonderful things that happen to your heart...
Rheumatic heart disease:
directly affect the heart but could lead to conditions that affect the heart or it's working in many ways. Rheumatic fever is one such condition that can first affect your throat and the connective tissues. If not treated at the right time it could...
Vitamin E and Heart disease:
Coronary artery disease is the term used to describe the gradual narrowing of the coronary arteries. The narrowing is caused by the building up of fatty deposits (atheroma) within the inner lining of the coronary arteries The atheroma contains...
|© heart-disease.com 2006|